Introduction
Hair
loss often starts with excessive hair fall, widened mid partition in females,
crown region thinning in males. People miss these signs as they turn into receding hairlines or even bald patches. Studies claim that
approximately half of the population suffers from pattern baldness irrespective
of gender. And regular treatments like minoxidil or finasteride often fall
short with their temporary relief and poor aesthetic outcomes.
The
latest research has introduced a new cutting-edge solution- the Exosome
Regenerative Therapy. It has transformed the field of aesthetic medicine with
its regenerative approach. It exploits the body’s own
communication tools to heal and regrow hair naturally.
Exosomes:
Nature's Messengers
Exosomes
are the messengers of the cell-cell communication network. These are tiny sacs
with a diameter of 30-150 nanometers that carry messages to nearby cells. The
messages are present in the form of biomolecules like
proteins, growth factors, lipids, and RNAs. They regulate the recipient cells
to respond accordingly.
However, messages
depend on the cells that form exosomes. Therefore, human umbilical cord-derived
mesenchymal stem cells are considered the gold standard for exosome source in
the cosmetic field. These are the Age
“0” cells of their biological timeline, with high regenerative potential,
which they transfer to exosomes.
5 Ways
Exosomes Impact Hair Growth
Decades
of scientific research have gone into the pathways
exosomes employ to drive hair restoration. The results not only outline the
multifaceted effects of exosome therapy but also establish them as an effective
solution for hair loss. Here’s how it helps:
Activate
Dormant Stem Cells
Although
they play a part in the new hair cycle, hair follicle stem cells decline in
number over time. Follicle regeneration is induced by exosomes, which promote
their activation and proliferation.
Prolong
Anagen Phase
Follicle
cycles occur in three phases. Anagen is the active growing phase, but many
factors shorten this phase and push follicles prematurely out of it. Exosome
treatment enhances the length and density of hair strands by extending this
Anagen phase.
Hair
Bulb Thickening
A
bulb is present in the follicle root and is composed of
dermal papillary cells. The diameter of the bulb defines the thickness of
strands. Exosomes promote the proliferation of dermal papillary cells to widen
the bulb region and increase strand thickness.
Nourish
Scalp
Hair
growth requires an adequate amount of nutrients and oxygen. By stimulating
blood vessel development (angiogenesis) exosome treatment enhances the
circulation of nutrients to the scalp, nourishes its health and supports
follicle growth.
Scalp
Environment
A
key reason for hair loss is the altered environment of scalp cells. The hair
loss is triggered by elevated levels of pro-inflammatory
cytokines, immune cells, and reactive oxygen species that interfere with normal
hair follicle growth. Exosomes lower the levels of pro-inflammatory cytokines,
inhibit the ROS and shift the environment towards repair, revive and regeneration.
All
these molecular events contribute to the standout performance of Exosomes at
the cellular level.Their 5-in-1 action doesn’t only alleviate the
symptoms but targets the root cause of hair loss.
What
are the Expected Results from Exosome Therapy?
The
reasons why exosomes are gaining the edge over other
treatments are their visible results. People undergoing exosome therapy notice
the following changes:
●
Reduced hair
fall
●
Increase in
hair regrowth and hair density
●
More scalp
coverage
●
Thicker and
longer strands
●
Improvement
of scalp health
Is
Exosome Hair Loss Therapy Safe?
Does
exosome therapy cause any complications? This question has
been asked many times. Several clinical studies are estimating the
effectiveness and safety of exosome therapy to answer these questions. In a
study, scientists treated 39 patients suffering from alopecia areata with
exosome therapy. At the end of the study, they found an increase in strand
density from 121 hairs/cm2 to 146 hairs/cm2. Moreover, none of the patients in
the study showed any adverse effects of the therapy. More such studies designed
on larger populations and longer terms will accurately answer the questions.
However, the early clinical trials do not reveal any hints of side effects
associated with the therapy.
Perks
of Exosome Therapy
Apart
from its effects on follicles, exosomes have grown in popularity due to the
following benefits:
●
Natural Solution: Exosomes are present naturally in the body. They contain
the natural biomolecules instead of additives, synthetic molecules, or harsh
chemicals.
●
Versatile: Exosomes can be applied to different types of hair
loss. Its applications even extend to skin treatments as well.
●
Diverse Repertoire: The bioactive ingredients of exosomes comprises not only
nourishing growth factors, proteins, peptides, lipids but also RNAs that revive
and regenerate cells from their core.
●
Preventive Measures: Exosomes not only regenerate but also reduce the process
that can cause damage in the future, thereby alleviating
the effect on hair loss triggers.
●
Deep & Lasting Effects: Most therapies only have superficial and modest
effects, whereas exosomes influence the follicles at the molecular and cellular
level for longer-lasting improvements.
●
Growth Factors: Exosomes contain growth factors exceeding any other therapies in the market.
●
Aesthetically Pleasing Outcomes: Exosomes induce the inherent healing pathways
present in the hair follicle cells, which lead to increased scalp coverage that
appears natural and aesthetically pleasing.
●
Minimally Invasive: Exosomes are administered in a minimally invasive manner,
requiring shorter downtime.
●
Health-Focused: The goal of this therapy is not to
prevent hair loss but to revitalize scalp health, which eventually regenerates
hair follicles and promotes hair growth.
●
Holistic Effects: While most treatments focus on one or two pathways of
hair loss or growth, exosomes act on a multitude of
pathways, tackling concerns from different directions.
Conclusion
Hair
fibres are the core elements of an individual’s persona. Hair loss, therefore,
affects a person’s perception of themselves and society. Among the many
treatments available in the market, exosome therapy is climbing to the top. It exploits the body’s own messengers to regenerate
follicles. Years of scientific research also support this therapy after pouring
tremendous efforts into exploring its effects.
The
visible outcomes of exosomes like - increased scalp coverage with longer,
thicker, and healthier strands have fascinated the cosmetic market. Their
holistic approach, natural-looking results, and molecular-level action
rejuvenate the scalp from within. In India, Advancexo has
made these remarkable exosomes accessible through its Hair Rejuve kit.